Risley is a neighbourhood in the northeast corner of Warrington, Cheshire, England.
It is south of Culcheth and is bordered to its north by the M62 motorway. During the Second World War it was the location of a Royal Ordnance Factory, ROF Risley. After the war it became the site of the design offices for the United Kingdom's fledgling nuclear weapons and nuclear power programmes. Universities Research Reactor was operational in Risley until 1991. Today the bulk of the area forms the new town of Birchwood.
HMP Risley is located in the area. the institution opened as a Remand Centre in 1964, but is now a Category C prison for adult males.